Harris, 55, was announced as Biden's choice to join the Democratic ticket on Tuesday afternoon after months of mounting speculation.
The Biden-Harris campaign will now run against President Donald Trump and Vice President Mike Pence in the Nov. 3 election.
Trump posted an attack ad on Harris soon after Biden's announcement on Tuesday. The ad labeled Harris as "radical," a familiar criticism Trump has used to describe Democrats. Later Tuesday he told reporters that, during the Democratic primary campaign, Harris had been "disrespectful" and "nasty" to Biden.
In late July, however, he said that Harris "would be a fine choice" by the former vice president.
"I’ve known Senator Harris for a long time," he said. "She is more than prepared for the job. She’s spent her career defending our Constitution and fighting for folks who need a fair shake."
The former president added: "Her own life story is one that I and so many others can see ourselves in: a story that says that no matter where you come from, what you look like, how you worship, or who you love, there’s a place for you here. It’s a fundamentally American perspective, one that’s led us out of the hardest times before. And it’s a perspective we can all rally behind right now."
Harris will become the first Black woman and the first Asian-American to join either major political party's presidential ticket.
Harris was named one of PEOPLE's Women Changing the World in 2019 along with Sens. Amy Klobuchar and Elizabeth Warren, all three of whom were leading a historic number of female presidential candidates.
“I think it’s really important for America to just have further evidence of the breadth and depth of what women are and what we can do," Harris told PEOPLE last year.
“Each woman who breaks a barrier and expands the minds of people in terms of what’s possible and what that looks like, they do our country a great service,” Harris said then. “I certainly do think about it that way.”
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